Peer Reviewed Publications

The Spine Journal

Howard An, M.D. leads a team of researchers who found that transplanting dermal fibroblasts can significantly increase the markers of disc regeneration and supported the hypothesis that the intervertebral disc is immune privileged. The study also suggests that fibroblast cell therapies can prevent the degeneration and promote the regeneration of the spinal disc.

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Global Spine Journal

A team of scientists led by Howard An, M.D. proves human dermal fibroblasts are a promising future for treatment of degenerative disc disease.

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Global Spine Journal

Journal of Translational Medicine

Our Chief Scientific Officer, Thomas Ichim, Ph.D. led a team in a thorough analysis of the advantage fibroblasts exhibit over mesenchymal stem cells.

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Journal of Translational Medicine Article

Rice Research Article

Under the direction of Antonios Mikos, Ph.D., human dermal fibroblasts were successfully differentiated into chondrocytes in an environment which simulated the spine. Read More



Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer - Read Article

Regulation of Hepatocyte Growth Factor Secretion by Fibroblasts in Patients With Acute Lung Injury - Read Article


Summary of new findings showing Fibroblasts act as potent immune cells to protect us against infectious diseases - Read Article

Fibroblasts can be potent suppressors of inflammation in arthritis - Read Article

Researchers show Fibroblasts can suppress pancreatic cancer - Read Article

Fibroblast Transplantation Results to the Degenerate Rabbit Lumbar Intervertebral Discs - Read Article


Fibroblast Transplantation Results to the Degenerate Rabbit Lumbar Intervertebral Discs - Read Article

Fibroblast Heterogeneity and Immunosuppressive Environment in Huma Breast Cancer - Read Article

Use Of FGF-2 and FGF-18 To Direct Bone Marrow Stromal Stem Cells To Chondrogenic and Osteogenic Lineages - Read Article

Erythropoietin-Producing Fibroblasts Facilitates Neurogenesis and Functional Recovery in an Ischemic Stroke Model - 

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Effects of Human Fibroblast-Derived Extracellular Matrix on Mesenchymal Stem Cells - Read Article

Reprogramming Mouse Embryo Fibroblasts to Functional Islets Without Genetic Manipulation - Read Article

Hepatocyte Growth Factor Produced in Lung Fibroblasts Enhances Non-Small Cell Lung Cancer Cell Survival and Tumor Progression

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